Neonatal Acute Compartment Syndrome as First Manifestation of Hematologic Disease: Case Report

Date of submission: 28-06-2020 | Date of acceptance: 22-12-2020 | Published: 02-07-2021

Authors

  • Maria Luís Sacras Pediatric Surgery Department, Hospital de Dona Estefânia, Centro Hospitalar Lisboa Central, Lisboa, Portugal
  • Catarina Ladeira Pediatric Surgery Department, Hospital de Dona Estefânia, Centro Hospitalar Lisboa Central, Lisboa, Portugal
  • Sara Carmo Pediatric Surgery Department, Hospital de Dona Estefânia, Centro Hospitalar Lisboa Central, Lisboa, Portugal
  • Paula Kjöllerström Hematology Unit, Hospital de Dona Estefânia, Centro Hospitalar Lisboa Central, Lisboa, Portugal

DOI:

https://doi.org/10.25754/pjp.2021.20470

Abstract

Hemophilia A, characterized by deficiency of functional plasma clotting factor VIII, is an X-linked disorder. Signs and symptoms depend on factor VIII levels. Severe hemophilia A (factor levels less than 1%) is usually diagnosed in the first two years of life. Pediatric compartment syndrome is most associated with trauma, but infectious and vascular causes must also be considered. We report a case of a newborn who presented with a severe hand hematoma after venous
puncture, complicated by compartment syndrome. An isolated prolonged partial thromboplastin time was found, and hemophilia was suspected. Factor VIII levels less than 1% were consistent with severe hemophilia A. The patient received recombinant factor VIII perioperatively. Fasciotomy was performed and the patient was kept on antibiotics until closure.

Downloads

Download data is not yet available.

Downloads

Published

2021-07-16

Issue

Section

Case reports

Most read articles by the same author(s)